This Mississippi Pot Roast is a comfort food classic made with real, whole ingredients-no premade seasoning packets here! Instead of MSG, gluten, or corn syrup, we're using simple spices, butter, and pepperoncini for incredible flavor. The result is tender, juicy chuck roast that practically melts in your mouth.

Why You'll Love This Recipe
- Clean ingredients - no packets, just real spices.
- Tender & flavorful - slow cooked until falling apart.
- Versatile cooking methods - Dutch oven or slow cooker.
- Keto & paleo friendly - hearty and satisfying without the junk.
How to cook Mississippi Pot Roast (Step by Step)
- 3lb chuck roast
- 1-2 tbsps. avocado oil
- 2 teaspoon salt
- 2 teaspoon pepper
- 1 stick of butter, or 8 tbsps.
- 12oz jar of pepperoncini, you want about half of the liquid from the jar and 6-8 pepperoncini
- 1 tbsp. dried parsley
- 1 tbsps. dried chives
- 1 tbsps. onion powder
- ½ tbsps. dried dill
- ½ tbsps. garlic powder
- ½ tbsps. salt
- ½ tbsps. pepper
- 2 bunches radishes
- 1 stalk celery
- 1 medium onion
Preheat your oven to 275 degrees.
Pour your oil into a Dutch oven and put it on the stove on medium heat. Season your roast with 2 teaspoon salt and 2 teaspoon of pepper, then place in the hot pan. Sear the meat for 6-7 minutes each side, or until you develop a nice brown sear. Take the meat out of the pot and set on a plate to the side.

While your roast is searing, chop up all of your vegetables into large dice sized pieces.

Throw in all of your vegetables. You might add a little more oil at this point. Scrape off all of the brown at the bottom of the pan as you stir the vegetables. Sauté for 7-9 minutes.
Push the vegetables to the side and place the roast in the middle. Put the rest of the ingredients on top (butter, pepperoncini, and seasoning).


Put the lid on the Dutch oven and place in the preheated oven for 3-4 hours, or until the meat is falling apart. It should shred easily once you take it out of the oven.


Storage & Reheat
- Fridge: Store leftovers in an airtight container for up to 4 days.
- Freezer: Freeze shredded pot roast with sauce for up to 3 months. Thaw overnight in the fridge before reheating.
- Reheat: Warm gently on the stovetop with a splash of broth or water, or microwave in short intervals until heated through.
FAQ
What cut of beef is best for Mississippi Pot Roast?
Chuck roast works best because it's well-marbled and tenderizes beautifully with slow cooking.
Can I make this without pepperoncini?
Yes, though the flavor will be less tangy. You can substitute banana peppers or add a splash of vinegar.
Can I make it dairy-free?
Yes - swap butter for ghee or a dairy-free butter alternative.
What can I serve it with?
Mashed cauliflower, roasted green beans, or a simple side salad pair perfectly.

Mississippi Pot Roast (Keto, Paleo, Gluten Free) Recipe
This Mississippi Pot Roast is a comfort food classic made from scratch — no premade packets! Tender chuck roast is slow-cooked with butter, pepperoncini, and a homemade blend of seasonings. Keto, paleo, and gluten-free, this version is hearty, flavorful, and made with real ingredients you can feel good about.
Ingredients
- 3 lb chuck roast
- 1-2 tbsps. avocado oil
- 2 teaspoon salt
- 2 teaspoon pepper
- 1 stick of butter, or 8 tbsps.
- 12oz jar of pepperoncini, you want about half of the liquid from the jar and 6-8 pepperoncini
- 1 tbsp. dried parsley
- 1 tbsps. dried chives
- 1 tbsps. onion powder
- ½ tbsps. dried dill
- ½ tbsps. garlic powder
- ½ tbsps. salt
- ½ tbsps. pepper
- 2 bunches radishes
- 1 stalk celery
- 1 medium onion
Instructions
- Preheat oven to 275°F.
- Heat avocado oil in a Dutch oven over medium heat. Season roast with 2 teaspoon salt and 2 teaspoon pepper, then sear 6–7 minutes per side until browned. Remove and set aside.
- Add chopped radishes, celery, and onion to the pot (add more oil if needed). Scrape up browned bits and sauté 7–9 minutes.
- Push veggies to the side, return roast to the pot, and top with butter, pepperoncini, pepperoncini liquid, and all seasonings.
- Cover with lid and bake 3–4 hours, until roast is fork-tender and shreds easily.
- Slow Cooker Option: Skip searing/sautéing. Place everything in the crockpot and cook on low 8–10 hours.
Notes
- Chuck roast is the best cut, but brisket or round roast also work.
- Pepperoncini adds tangy flavor — substitute banana peppers if needed.
- Make it dairy-free with ghee or plant-based butter.
- Serve with mashed cauliflower, green beans, or over rice (if not keto).
Nutrition Information:
Yield: 6 Serving Size: 1Amount Per Serving: Calories: 765Total Fat: 55gSaturated Fat: 25gTrans Fat: 3gUnsaturated Fat: 27gCholesterol: 229mgSodium: 3467mgCarbohydrates: 12gFiber: 3gSugar: 6gProtein: 58g
The nutrition information for this recipe is an approximate total per serving. Please double check the nutrition information for your exact ingredients and brands for more precise nutrition information.
More Delicious Beef Recipes!
If you loved this Mississippi Pot Roast, here are more hearty beef recipes to try:
- Light Chinese Beef Stew (清燉牛肉): A clear-broth beef stew made with beef shank, ginger, and green onions. Comforting and savory without being heavy.
- Slow Cooker Chinese Braised Beef Stew: Traditional red-braised beef, this version simmers in a slow cooker until melt-in-your-mouth tender.
- Taiwanese Beef Noodle Soup (紅燒牛肉麵): The ultimate comfort food - tender braised beef, rich broth, and chewy noodles in a classic Taiwanese favorite.
- Stir Fry Ground Beef: Quick and easy stir fry with ground beef, garlic, onions, and mushrooms - a flavorful 20-minute dinner.
Pin for later!






linda spiker says
I haven't made a pot roast in forever. Thanks for the step by step, very helpful.
paleoglutenfreeguy says
I love the addition of pepperoncini! Totally elevates this from the usual boring pot roast.
Jo says
I can already tell this roast is going to be delicious and can't wait to try it. I love dill with my meat and LOVE that it's got a ton of butter. I'm drooling!
Raia Todd says
Mmmm.... that is some serious comfort food there! SO delicious!
Daniela says
This is mouthwatering! I really love the creative use of radishes in this dish!